Cargando…

Aster saponin A(2) inhibits osteoclastogenesis through mitogen-activated protein kinase-c-Fos-NFATc1 signaling pathway

BACKGROUND: In lipopolysaccharide-induced RAW264.7 cells, Aster tataricus (AT) inhibits the nuclear factor kappa-light-chain-enhancer of activated B cells and MAPKs pathways and critical pathways of osteoclast development and bone resorption. OBJECTIVES: This study examined how aster saponin A2 (AS-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Su, Xiang-Dong, Yang, Seo Y, Shrestha, Saroj K, Soh, Yunjo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Veterinary Science 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346523/ https://www.ncbi.nlm.nih.gov/pubmed/35698806 http://dx.doi.org/10.4142/jvs.21246

Ejemplares similares

Ginsenoside Rg2 inhibits osteoclastogenesis by downregulating the NFATc1, c-Fos, and MAPK pathways
por: Lee, Sung-Hoon, et al.
Publicado: (2023)

Gleditsiae fructus regulates osteoclastogenesis by inhibiting the c‑Fos/NFATc1 pathway and alleviating bone loss in an ovariectomy model
por: Cho, Chang-Young, et al.
Publicado: (2023)

Suppression of Inflammation, Osteoclastogenesis and Bone Loss by PZRAS Extract
por: Li, Liang, et al.
Publicado: (2020)

BHLHE40 promotes osteoclastogenesis and abnormal bone resorption via c-Fos/NFATc1
por: Zhang, Yufeng, et al.
Publicado: (2022)

Parthenolide inhibits osteoclast differentiation and bone resorbing activity by down-regulation of NFATc1 induction and c-Fos stability, during RANKL-mediated osteoclastogenesis
por: Kim, Ju-Young, et al.
Publicado: (2014)

Wedelolactone enhances osteoblastogenesis by regulating Wnt/β-catenin signaling pathway but suppresses osteoclastogenesis by NF-κB/c-fos/NFATc1 pathway
por: Liu, Yan-Qiu, et al.
Publicado: (2016)

Umbelliferone Prevents Lipopolysaccharide-Induced Bone Loss and Suppresses RANKL-Induced Osteoclastogenesis by Attenuating Akt-c-Fos-NFATc1 Signaling
por: Kwak, Sung Chul, et al.
Publicado: (2019)

Agelasine D Suppresses RANKL-Induced Osteoclastogenesis via Down-Regulation of c-Fos, NFATc1 and NF-κB
por: Kang, Moo Rim, et al.
Publicado: (2014)

An Autophagy Inducing Triterpene Saponin Derived from Aster koraiensis
por: Kwon, Jaeyoung, et al.
Publicado: (2019)

Stauntonia hexaphylla (Lardizabalaceae) leaf methanol extract inhibits osteoclastogenesis and bone resorption activity via proteasome-mediated degradation of c-Fos protein and suppression of NFATc1 expression
por: Cheon, Yoon-Hee, et al.
Publicado: (2015)

Kalkitoxin attenuates calcification of vascular smooth muscle cells via RUNX-2 signaling pathways
por: Shrestha, Saroj K, et al.
Publicado: (2023)

Genetic and pharmacological activation of Hedgehog signaling inhibits osteoclastogenesis and attenuates titanium particle-induced osteolysis partly through suppressing the JNK/c-Fos-NFATc1 cascade
por: Zhang, Liwei, et al.
Publicado: (2020)

Major vault protein (MVP) negatively regulates osteoclastogenesis via calcineurin-NFATc1 pathway inhibition
por: Yuan, Lichan, et al.
Publicado: (2021)

Fisetin Inhibits Osteoclast Differentiation via Downregulation of p38 and c-Fos-NFATc1 Signaling Pathways
por: Choi, Sik-Won, et al.
Publicado: (2012)

The Brown Algae Ishige sinicola Extract Ameliorates Ovariectomy-Induced Bone Loss in Rats and Suppresses Osteoclastogenesis through Downregulation of NFATc1/c-Fos
por: Kim, Mihyang, et al.
Publicado: (2022)

Dectin-1 signaling inhibits osteoclastogenesis via IL-33-induced inhibition of NFATc1
por: Zhu, Xiaoqing, et al.
Publicado: (2017)

Peiminine Suppresses RANKL-Induced Osteoclastogenesis by Inhibiting the NFATc1, ERK, and NF-κB Signaling Pathways
por: Zhu, Mengbo, et al.
Publicado: (2021)

Triptolide prevents bone loss via suppressing osteoclastogenesis through inhibiting PI3K‐AKT‐NFATc1 pathway
por: Cui, Jin, et al.
Publicado: (2020)

Dracorhodin perchlorate inhibits osteoclastogenesis through repressing RANKL‐stimulated NFATc1 activity
por: Liu, Yuhao, et al.
Publicado: (2020)

Adseverin mediates RANKL-induced osteoclastogenesis by regulating NFATc1
por: Song, Min-Kyoung, et al.
Publicado: (2015)

Interleukin-10 inhibits osteoclastogenesis by reducing NFATc1 expression and preventing its translocation to the nucleus
por: Evans, Kathryn E, et al.
Publicado: (2007)

Cytochalasin Z11 inhibits RANKL-induced osteoclastogenesis via suppressing NFATc1 activation
por: Wang, Lu, et al.
Publicado: (2019)

Babam2 negatively regulates osteoclastogenesis by interacting with Hey1 to inhibit Nfatc1 transcription
por: Jin, Fujun, et al.
Publicado: (2022)

Water extract of Cnidii Rhizoma suppresses RANKL-induced osteoclastogenesis in RAW 264.7 cell by inhibiting NFATc1/c-Fos signaling and prevents ovariectomized bone loss in SD-rat
por: Lee, Ka-Yeon, et al.
Publicado: (2019)

Corydalis Saxicola Bunting Total Alkaloids Attenuate Walker 256-Induced Bone Pain and Osteoclastogenesis by Suppressing RANKL-Induced NF-κB and c-Fos/NFATc1 Pathways in Rats
por: Ju, Linjie, et al.
Publicado: (2021)

Gα12 regulates osteoclastogenesis by modulating NFATc1 expression
por: Song, Min‐Kyoung, et al.
Publicado: (2017)

The Role of Ca(2+)-NFATc1 Signaling and Its Modulation on Osteoclastogenesis
por: Kang, Jung Yun, et al.
Publicado: (2020)

The Coumarin Derivative 5′-Hydroxy Auraptene Suppresses Osteoclast Differentiation via Inhibiting MAPK and c-Fos/NFATc1 Pathways
por: Abdallah, Basem M., et al.
Publicado: (2019)

Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway
por: Wu, Mengrui, et al.
Publicado: (2017)

The deubiquitinase UCHL1 negatively controls osteoclastogenesis by regulating TAZ/NFATC1 signalling
por: Feng, Zhenhua, et al.
Publicado: (2023)

Ethyl Acetate Fraction of Aqueous Extract of Lentinula edodes Inhibits Osteoclastogenesis by Suppressing NFATc1 Expression
por: Lee, Hyerim, et al.
Publicado: (2020)

Oat Seedlings Extract Inhibits RANKL-Induced c-Fos/NFATc1 Transcription Factors in the Early Stage of Osteoclast Differentiation
por: Yang, Ji Yeong, et al.
Publicado: (2022)

Transforming growth factor-β enables NFATc1 expression during osteoclastogenesis
por: Fox, S.W., et al.
Publicado: (2008)

Accelerated Lactate Dehydrogenase Activity Potentiates Osteoclastogenesis via NFATc1 Signaling
por: Ahn, Heejin, et al.
Publicado: (2016)

Betulinic Acid Protects From Bone Loss in Ovariectomized Mice and Suppresses RANKL-Associated Osteoclastogenesis by Inhibiting the MAPK and NFATc1 Pathways
por: Wei, Jiyong, et al.
Publicado: (2020)

Dehydrocostus lactone inhibits NFATc1 via regulation of IKK, JNK, and Nrf2, thereby attenuating osteoclastogenesis
por: Lee, Hye In, et al.
Publicado: (2020)

Inhibition of RANKL-stimulated osteoclast differentiation by Schisandra chinensis through down-regulation of NFATc1 and c-fos expression
por: Kim, Eun-Jung, et al.
Publicado: (2018)

Magnolol prevents ovariectomy-induced bone loss by suppressing osteoclastogenesis via inhibition of the nuclear factor-κB and mitogen-activated protein kinase pathways
por: Fei, Wen-Yong, et al.
Publicado: (2019)

Acteoside Suppresses RANKL-Mediated Osteoclastogenesis by Inhibiting c-Fos Induction and NF-κB Pathway and Attenuating ROS Production
por: Lee, Seung-Youp, et al.
Publicado: (2013)

Effects of aloe-emodin on alveolar bone in Porphyromonas gingivalis-induced periodontitis rat model: a pilot study
por: Yang, Ming, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_i8evjctgar2gt2gbg2u2cn93o3