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High sodium reduced the expression of PTH1R and Klotho by inhibiting 1,25(OH)(2)D(3) synthesis in cultured proximal tubule epithelial cells

BACKGROUND: The proximal tubule is the sensing site of sodium and phosphate and the main place for the synthesis and metabolism of 1,25(OH)(2)D(3). We aimed to investigate the effects of high sodium on the synthesis and function of active vitamin D and local phosphate regulation in proximal tubular...

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Detalles Bibliográficos
Autores principales:	Gu, Jie, Shi, Jialin, Chen, Xujiao, Mao, Jianping, You, Huaizhou, Chen, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347055/ https://www.ncbi.nlm.nih.gov/pubmed/35928745 http://dx.doi.org/10.21037/atm-21-5910

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