Targeting the radiation-induced ARv7-mediated circNHS/miR-512-5p/XRCC5 signaling with Quercetin increases prostate cancer radiosensitivity

BACKGROUND: Radiation therapy (RT) with androgen deprivation therapy (ADT) is an effective therapy to suppress the locally advanced prostate cancer (PCa). However, we unexpectedly found that RT could also induce the androgen receptor splice variant 7 (ARv7) expression to decrease the radiosensitivit...

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Detalles Bibliográficos
Autores principales: Chen, Dong, Chou, Fu-Ju, Chen, Yuhchyau, Huang, Chi-Ping, Tian, Hao, Wang, Yaqin, Niu, Yuanjie, You, Bosen, Yeh, Shuyuan, Xing, Nianzeng, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347162/
https://www.ncbi.nlm.nih.gov/pubmed/35918767
http://dx.doi.org/10.1186/s13046-022-02287-4

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