Cargando…

Alphaherpesvirus US3 protein-mediated inhibition of the m6A mRNA methyltransferase complex

Chemical modifications of mRNA, the so-called epitranscriptome, represent an additional layer of post-transcriptional regulation of gene expression. The most common epitranscriptomic modification, N6-methyladenosine (m6A), is generated by a multi-subunit methyltransferase complex. We show that alpha...

Descripción completa

Detalles Bibliográficos
Autores principales: Jansens, Robert J.J., Verhamme, Ruth, Mirza, Aashiq H., Olarerin-George, Anthony, Van Waesberghe, Cliff, Jaffrey, Samie R., Favoreel, Herman W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347262/
https://www.ncbi.nlm.nih.gov/pubmed/35858564
http://dx.doi.org/10.1016/j.celrep.2022.111107