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High Frequencies of Phenotypically and Functionally Senescent and Exhausted CD56(+)CD57(+)PD-1(+) Natural Killer Cells, SARS-CoV-2-Specific Memory CD4(+) and CD8(+) T cells Associated with Severe Disease in Unvaccinated COVID-19 Patients
Unvaccinated COVID-19 patients display a large spectrum of symptoms, ranging from asymptomatic to severe symptoms, the latter even causing death. Distinct Natural killer (NK) and CD4(+) and CD8(+) T cells immune responses are generated in COVID-19 patients. However, the phenotype and functional char...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347283/ https://www.ncbi.nlm.nih.gov/pubmed/35923316 http://dx.doi.org/10.1101/2022.07.26.501655 |