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Importance of two-dimensional cation clusters induced by protein folding in intrinsic intracellular membrane permeability

We investigated the cell penetration of Sp1 zinc finger proteins (Sp1 ZF) and the mechanism via which the total cationic charge and distribution of cationic residues on the protein surface affect intracellular trafficking. Sp1 ZFs showed intrinsic cell membrane permeability. The intracellular transf...

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Detalles Bibliográficos
Autores principales:	Negi, Shigeru, Hamori, Mami, Kawahara-Nakagawa, Yuka, Imanishi, Miki, Kurehara, Miku, Kitada, Chieri, Kawahito, Yuri, Kishi, Kanae, Manabe, Takayuki, Kawamura, Nobuyuki, Kitagishi, Hiroaki, Mashimo, Masato, Shibata, Nobuhito, Sugiura, Yukio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	RSC 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347356/ https://www.ncbi.nlm.nih.gov/pubmed/35975000 http://dx.doi.org/10.1039/d2cb00098a

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