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Utilization of propranolol hydrochloride mucoadhesive invasomes as a locally acting contraceptive: in-vitro, ex-vivo, and in-vivo evaluation

It was found that propranolol hydrochloride (PNL), which is a beta-blocker used for hypertension treatment, has a potent spermicidal activity through local anesthetic activity or beta-blocking effect on sperm cells subsequently it could be used as a contraceptive remedy. This study aimed to entrap P...

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Detalles Bibliográficos
Autores principales: Teaima, Mahmoud H., Eltabeeb, Moaz A., El-Nabarawi, Mohamed A., Abdellatif, Menna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9347470/
https://www.ncbi.nlm.nih.gov/pubmed/35912869
http://dx.doi.org/10.1080/10717544.2022.2100514