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Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Down syndrome (DS) is caused by human chromosome 21 (HSA21) trisomy. It is characterized by a poorly understood intellectual disability (ID). We studied two mouse models of DS, one with an extra copy of the Dyrk1A gene (189N3) and the other with an extra copy of the mouse Chr16 syntenic region (Dp(1...

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Detalles Bibliográficos
Autores principales:	Viard, Julia, Loe-Mie, Yann, Daudin, Rachel, Khelfaoui, Malik, Plancon, Christine, Boland, Anne, Tejedor, Francisco, Huganir, Richard L, Kim, Eunjoon, Kinoshita, Makoto, Liu, Guofa, Haucke, Volker, Moncion, Thomas, Yu, Eugene, Hindie, Valérie, Bléhaut, Henri, Mircher, Clotilde, Herault, Yann, Deleuze, Jean-François, Rain, Jean-Christophe, Simonneau, Michel, Lepagnol-Bestel, Aude-Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348576/ https://www.ncbi.nlm.nih.gov/pubmed/35914814 http://dx.doi.org/10.26508/lsa.202101205

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