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Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model

Quantitative systems pharmacology (QSP) models and spatial agent-based models (ABM) are powerful and efficient approaches for the analysis of biological systems and for clinical applications. Although QSP models are becoming essential in discovering predictive biomarkers and developing combination t...

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Detalles Bibliográficos
Autores principales:	Ruiz-Martinez, Alvaro, Gong, Chang, Wang, Hanwen, Sové, Richard J., Mi, Haoyang, Kimko, Holly, Popel, Aleksander S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348712/ https://www.ncbi.nlm.nih.gov/pubmed/35867773 http://dx.doi.org/10.1371/journal.pcbi.1010254

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