Broadly neutralizing antibodies target the coronavirus fusion peptide

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The potential for future coronavirus outbreaks highlights the need to broadly target this group of pathogens. We use an epitope-agnostic approach to identify six monoclonal antibodies that bind to spike proteins from all seven human-infecting coronaviruses. All six antibodies target the conserved fu...

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Detalles Bibliográficos
Autores principales: Dacon, Cherrelle, Tucker, Courtney, Peng, Linghang, Lee, Chang-Chun D., Lin, Ting-Hui, Yuan, Meng, Cong, Yu, Wang, Lingshu, Purser, Lauren, Williams, Jazmean K., Pyo, Chul-Woo, Kosik, Ivan, Hu, Zhe, Zhao, Ming, Mohan, Divya, Cooper, Andrew J. R., Peterson, Mary, Skinner, Jeff, Dixit, Saurabh, Kollins, Erin, Huzella, Louis, Perry, Donna, Byrum, Russell, Lembirik, Sanae, Drawbaugh, David, Eaton, Brett, Zhang, Yi, Yang, Eun Sung, Chen, Man, Leung, Kwanyee, Weinberg, Rona S., Pegu, Amarendra, Geraghty, Daniel E., Davidson, Edgar, Douagi, Iyadh, Moir, Susan, Yewdell, Jonathan W., Schmaljohn, Connie, Crompton, Peter D., Holbrook, Michael R., Nemazee, David, Mascola, John R., Wilson, Ian A., Tan, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348754/
https://www.ncbi.nlm.nih.gov/pubmed/35857439
http://dx.doi.org/10.1126/science.abq3773

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