Hyperresponsive cytosolic DNA-sensing pathway in monocytes from primary Sjögren’s syndrome

OBJECTIVES: Cytosolic DNA-sensing pathway stimulation prompts type I IFN (IFN-I) production, but its role in systemic IFN-I pathway activation in primary SS (pSS) is poorly studied. Here we investigate the responsiveness of pSS monocytes and plasmacytoid dendritic cells (pDCs) to stimulator of inter...

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Detalles Bibliográficos
Autores principales: Huijser, Erika, Bodewes, Iris L A, Lourens, Mirthe S, van Helden-Meeuwsen, Cornelia G, van den Bosch, Thierry P P, Grashof, Dwin G B, van de Werken, Harmen J G, Lopes, Ana P, van Roon, Joel A G, van Daele, Paul L A, Brkic, Zana, Dik, Willem A, Versnel, Marjan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348764/
https://www.ncbi.nlm.nih.gov/pubmed/35022662
http://dx.doi.org/10.1093/rheumatology/keac016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348764/
https://www.ncbi.nlm.nih.gov/pubmed/35022662
http://dx.doi.org/10.1093/rheumatology/keac016

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