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Cell surface SARS-CoV-2 nucleocapsid protein modulates innate and adaptive immunity

SARS-CoV-2 nucleocapsid protein (N) induces strong antibody (Ab) and T cell responses. Although considered to be localized in the cytosol, we readily detect N on the surface of live cells. N released by SARS-CoV-2–infected cells or N-expressing transfected cells binds to neighboring cells by electro...

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Detalles Bibliográficos
Autores principales: López-Muñoz, Alberto Domingo, Kosik, Ivan, Holly, Jaroslav, Yewdell, Jonathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348789/
https://www.ncbi.nlm.nih.gov/pubmed/35921414
http://dx.doi.org/10.1126/sciadv.abp9770

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