Cross-species identification of cancer resistance–associated genes that may mediate human cancer risk

Cancer is a predominant disease across animals. We applied a comparative genomics approach to systematically characterize genes whose conservation levels correlate positively (PC) or negatively (NC) with cancer resistance estimates across 193 vertebrates. Pathway analysis reveals that NC genes are e...

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Detalles Bibliográficos
Autores principales: Nair, Nishanth Ulhas, Cheng, Kuoyuan, Naddaf, Lamis, Sharon, Elad, Pal, Lipika R., Rajagopal, Padma S., Unterman, Irene, Aldape, Kenneth, Hannenhalli, Sridhar, Day, Chi-Ping, Tabach, Yuval, Ruppin, Eytan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348801/
https://www.ncbi.nlm.nih.gov/pubmed/35921407
http://dx.doi.org/10.1126/sciadv.abj7176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348801/
https://www.ncbi.nlm.nih.gov/pubmed/35921407
http://dx.doi.org/10.1126/sciadv.abj7176

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