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Cross-species identification of cancer resistance–associated genes that may mediate human cancer risk
Cancer is a predominant disease across animals. We applied a comparative genomics approach to systematically characterize genes whose conservation levels correlate positively (PC) or negatively (NC) with cancer resistance estimates across 193 vertebrates. Pathway analysis reveals that NC genes are e...
Autores principales: | Nair, Nishanth Ulhas, Cheng, Kuoyuan, Naddaf, Lamis, Sharon, Elad, Pal, Lipika R., Rajagopal, Padma S., Unterman, Irene, Aldape, Kenneth, Hannenhalli, Sridhar, Day, Chi-Ping, Tabach, Yuval, Ruppin, Eytan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348801/ https://www.ncbi.nlm.nih.gov/pubmed/35921407 http://dx.doi.org/10.1126/sciadv.abj7176 |
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