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Case Report: Two Patients With EGFR Exon 20 Insertion Mutanted Non-Small Cell Lung Cancer Precision Treatment Using Patient-Derived Xenografts in Zebrafish Embryos

BACKGROUND: Epidermal growth factor receptor (EGFR) exon 20 insertion mutations are uncommon EGFR mutations and generally resistant to first- and second-generation EGFR-tyrosine kinase inhibitors (TKIs). In precision oncology, treatment regimens are tested for improving the clinical outcomes. Zebraf...

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Detalles Bibliográficos
Autores principales:	Wang, Qian, Wang, Wenxian, Pan, Weiwei, Lv, Xiaojing, Zhang, Lei, Zheng, Kaiming, Tian, Fang, Xu, Chunwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9348893/ https://www.ncbi.nlm.nih.gov/pubmed/35936715 http://dx.doi.org/10.3389/fonc.2022.884798

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