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Measuring the density of the fissula antefenestram and the section of the basal turn of the cochlea: Are they useful in the radiological diagnosis of otosclerosis?

INTRODUCTION: The role of objective parameters in terms of improvement of the accuracy of high-resolution computed tomography (HRCT) of the temporal bone in the diagnosis of otosclerosis remains unclear. OBJECTIVES: To investigate the relationship between the density of the fissula antefenestram (FA...

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Autores principales: Resende Lucinda Mangia, Lucas, Lucca de Oliveira Salvador, Gabriel, Carvalho, Bettina, Hamerschmidt, Rogério
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese PLA General Hospital 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349010/
https://www.ncbi.nlm.nih.gov/pubmed/35949553
http://dx.doi.org/10.1016/j.joto.2022.01.001
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author Resende Lucinda Mangia, Lucas
Lucca de Oliveira Salvador, Gabriel
Carvalho, Bettina
Hamerschmidt, Rogério
author_facet Resende Lucinda Mangia, Lucas
Lucca de Oliveira Salvador, Gabriel
Carvalho, Bettina
Hamerschmidt, Rogério
author_sort Resende Lucinda Mangia, Lucas
collection PubMed
description INTRODUCTION: The role of objective parameters in terms of improvement of the accuracy of high-resolution computed tomography (HRCT) of the temporal bone in the diagnosis of otosclerosis remains unclear. OBJECTIVES: To investigate the relationship between the density of the fissula antefenestram (FAF) and of the width of the transversal section of the basal turn of the cochlea (BTC), and the diagnosis of otosclerosis. METHODS: This is a retrospective study in which preoperative HRCT data from ears of patients submitted to stapedotomy due to otosclerosis (case group) were evaluated. For the control group, normal hearing ears having undergone HRCT for other purposes were included. Case and control HRCT images were objectively assessed by an experienced blinded radiologist. During this evaluation, measurements of the relative radiological density of the FAF and of the transversal section of the BTC were obtained. The results were compared between the groups. Also, a receiver operating characteristic curve was created and the area under the curve (AUC) was calculated for each variable. Significance level was set at .05. RESULTS: 40 ears were included in each group. Case ears presented reduced values for the relative radiological density on the FAF (p-value<0.0001). Moreover, ears with otosclerosis (p-value: 0.022) presented lower transversal section of the BTC. The AUC for these variables reached 0.929 and 0.646, respectively. CONCLUSIONS: Otosclerotic ears present reduced radiological density on the FAF and narrower BTC. The relative density of the FAF also shows a great diagnostic power in the context of this disease.
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spelling pubmed-93490102022-08-09 Measuring the density of the fissula antefenestram and the section of the basal turn of the cochlea: Are they useful in the radiological diagnosis of otosclerosis? Resende Lucinda Mangia, Lucas Lucca de Oliveira Salvador, Gabriel Carvalho, Bettina Hamerschmidt, Rogério J Otol Research Article INTRODUCTION: The role of objective parameters in terms of improvement of the accuracy of high-resolution computed tomography (HRCT) of the temporal bone in the diagnosis of otosclerosis remains unclear. OBJECTIVES: To investigate the relationship between the density of the fissula antefenestram (FAF) and of the width of the transversal section of the basal turn of the cochlea (BTC), and the diagnosis of otosclerosis. METHODS: This is a retrospective study in which preoperative HRCT data from ears of patients submitted to stapedotomy due to otosclerosis (case group) were evaluated. For the control group, normal hearing ears having undergone HRCT for other purposes were included. Case and control HRCT images were objectively assessed by an experienced blinded radiologist. During this evaluation, measurements of the relative radiological density of the FAF and of the transversal section of the BTC were obtained. The results were compared between the groups. Also, a receiver operating characteristic curve was created and the area under the curve (AUC) was calculated for each variable. Significance level was set at .05. RESULTS: 40 ears were included in each group. Case ears presented reduced values for the relative radiological density on the FAF (p-value<0.0001). Moreover, ears with otosclerosis (p-value: 0.022) presented lower transversal section of the BTC. The AUC for these variables reached 0.929 and 0.646, respectively. CONCLUSIONS: Otosclerotic ears present reduced radiological density on the FAF and narrower BTC. The relative density of the FAF also shows a great diagnostic power in the context of this disease. Chinese PLA General Hospital 2022-04 2022-01-06 /pmc/articles/PMC9349010/ /pubmed/35949553 http://dx.doi.org/10.1016/j.joto.2022.01.001 Text en © 2022 PLA General Hospital Department of Otolaryngology Head and Neck Surgery. Production and hosting by Elsevier (Singapore) Pte Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Article
Resende Lucinda Mangia, Lucas
Lucca de Oliveira Salvador, Gabriel
Carvalho, Bettina
Hamerschmidt, Rogério
Measuring the density of the fissula antefenestram and the section of the basal turn of the cochlea: Are they useful in the radiological diagnosis of otosclerosis?
title Measuring the density of the fissula antefenestram and the section of the basal turn of the cochlea: Are they useful in the radiological diagnosis of otosclerosis?
title_full Measuring the density of the fissula antefenestram and the section of the basal turn of the cochlea: Are they useful in the radiological diagnosis of otosclerosis?
title_fullStr Measuring the density of the fissula antefenestram and the section of the basal turn of the cochlea: Are they useful in the radiological diagnosis of otosclerosis?
title_full_unstemmed Measuring the density of the fissula antefenestram and the section of the basal turn of the cochlea: Are they useful in the radiological diagnosis of otosclerosis?
title_short Measuring the density of the fissula antefenestram and the section of the basal turn of the cochlea: Are they useful in the radiological diagnosis of otosclerosis?
title_sort measuring the density of the fissula antefenestram and the section of the basal turn of the cochlea: are they useful in the radiological diagnosis of otosclerosis?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349010/
https://www.ncbi.nlm.nih.gov/pubmed/35949553
http://dx.doi.org/10.1016/j.joto.2022.01.001
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