Safety, Pharmacodynamics, and Pharmacokinetics of P2X3 Receptor Antagonist Eliapixant (BAY 1817080) in Healthy Subjects: Double-Blind Randomized Study

BACKGROUND AND OBJECTIVE: There is no licensed treatment for refractory chronic cough; off-label therapies have limited efficacy and can produce adverse effects. Excessive adenosine triphosphate signaling via P2X3 receptors is implicated in refractory chronic cough, and selective P2X3 receptor antag...

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Detalles Bibliográficos
Autores principales: Friedrich, Christian, Francke, Klaus, Gashaw, Isabella, Scheerans, Christian, Klein, Stefan, Fels, Lueder, Smith, Jaclyn A., Hummel, Thomas, Morice, Alyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349145/
https://www.ncbi.nlm.nih.gov/pubmed/35624408
http://dx.doi.org/10.1007/s40262-022-01126-1

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