Cargando…

Ciprofloxacin Pharmacokinetics After Oral and Intravenous Administration in (Morbidly) Obese and Non-obese Individuals: A Prospective Clinical Study

BACKGROUND AND OBJECTIVE: Ciprofloxacin is a fluoroquinolone used for empirical and targeted therapy of a wide range of infections. Despite the increase in obesity prevalence, only very limited guidance is available on whether the ciprofloxacin dose needs to be adjusted when administered orally or i...

Descripción completa

Detalles Bibliográficos
Autores principales:	van Rhee, Koen P., Smit, Cornelis, Wasmann, Roeland E., van der Linden, Paul D., Wiezer, Rene, Van Dongen, Eric P. A., Krekels, Elke H. J., Brüggemann, Roger J. M., Knibbe, Catherijne A. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349153/ https://www.ncbi.nlm.nih.gov/pubmed/35641862 http://dx.doi.org/10.1007/s40262-022-01130-5

Ejemplares similares

Population pharmacokinetics of vancomycin in obesity: Finding the optimal dose for (morbidly) obese individuals
por: Smit, Cornelis, et al.
Publicado: (2020)

Fixed Dosing of Liposomal Amphotericin B in Morbidly Obese Individuals
por: Wasmann, Roeland E, et al.
Publicado: (2020)

Tobramycin Clearance Is Best Described by Renal Function Estimates in Obese and Non-obese Individuals: Results of a Prospective Rich Sampling Pharmacokinetic Study
por: Smit, Cornelis, et al.
Publicado: (2019)

A Prospective Clinical Study Characterizing the Influence of Morbid Obesity on the Pharmacokinetics of Gentamicin: Towards Individualized Dosing in Obese Patients
por: Smit, Cornelis, et al.
Publicado: (2019)

Implications for IV posaconazole dosing in the era of obesity
por: Wasmann, Roeland E, et al.
Publicado: (2020)

Vancomycin Clearance in Obese Adults is not Predictive of Clearance in Obese Adolescents
por: Zhang, Tan, et al.
Publicado: (2023)

Midazolam Pharmacokinetics in Morbidly Obese Patients Following Semi-Simultaneous Oral and Intravenous Administration: A Comparison with Healthy Volunteers
por: Brill, Margreke J. E., et al.
Publicado: (2014)

Dose recommendations for gentamicin in the real-world obese population with varying body weight and renal (dys)function
por: Smit, Cornelis, et al.
Publicado: (2020)

Higher Midazolam Clearance in Obese Adolescents Compared with Morbidly Obese Adults
por: van Rongen, Anne, et al.
Publicado: (2017)

Influence of Morbid Obesity on the Pharmacokinetics of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide
por: de Hoogd, Sjoerd, et al.
Publicado: (2017)

The Pharmacokinetics of the CYP3A Substrate Midazolam in Morbidly Obese Patients Before and One Year After Bariatric Surgery
por: Brill, Margreke J., et al.
Publicado: (2015)

Dosing Recommendations for Vancomycin in Children and Adolescents with Varying Levels of Obesity and Renal Dysfunction: a Population Pharmacokinetic Study in 1892 Children Aged 1–18 Years
por: Smit, Cornelis, et al.
Publicado: (2021)

Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen
por: van Rongen, Anne, et al.
Publicado: (2016)

Clinical Pharmacokinetics and Pharmacodynamics of Micafungin
por: Wasmann, Roeland E., et al.
Publicado: (2017)

The Predictive Value of Glomerular Filtration Rate-Based Scaling of Pediatric Clearance and Doses for Drugs Eliminated by Glomerular Filtration with Varying Protein-Binding Properties
por: Cristea, Sinziana, et al.
Publicado: (2020)

Pharmacokinetics and Pharmacodynamics of Posaconazole
por: Chen, Lu, et al.
Publicado: (2020)

An Integrated Population Pharmacokinetic Meta-Analysis of Propofol in Morbidly Obese and Nonobese Adults, Adolescents, and Children
por: Diepstraten, J, et al.
Publicado: (2013)

Evaluation of propofol anesthesia in morbidly obese children and adolescents
por: Chidambaran, Vidya, et al.
Publicado: (2013)

Systematic Evaluation of the Descriptive and Predictive Performance of Paediatric Morphine Population Models
por: Krekels, Elke H. J., et al.
Publicado: (2010)

Children Are Not Small Adults, but Can We Treat Them As Such?
por: Krekels, Elke H.J., et al.
Publicado: (2019)

Increased Arterial Stiffness in Adolescents With Obesity
por: Lentferink, Yvette E., et al.
Publicado: (2019)

Towards Evidence-Based Weaning: a Mechanism-Based Pharmacometric Model to Characterize Iatrogenic Withdrawal Syndrome in Critically Ill Children
por: Goulooze, Sebastiaan C., et al.
Publicado: (2021)

Predictors of Insulin Resistance in Children versus Adolescents with Obesity
por: Lentferink, Yvette E., et al.
Publicado: (2017)

Inflammatory T-lymphocyte proliferation in morbid obesity
por: Van der Weerd, K, et al.
Publicado: (2010)

Impact of mucositis on oral bioavailability and systemic exposure of ciprofloxacin Gram-negative infection prophylaxis in patients with haematological malignancies
por: van Rhee, K P, et al.
Publicado: (2022)

Developmental changes rather than repeated administration drive paracetamol glucuronidation in neonates and infants
por: Krekels, Elke H. J., et al.
Publicado: (2015)

Supervised Multidimensional Item Response Theory Modeling of Pediatric Iatrogenic Withdrawal Symptoms
por: Goulooze, Sebastiaan C., et al.
Publicado: (2019)

Dose‐linearity of the pharmacokinetics of an intravenous [(14)C]midazolam microdose in children
por: van Groen, Bianca D., et al.
Publicado: (2019)

Does Weight Impact Anidulafungin Pharmacokinetics?
por: Lempers, Vincent J., et al.
Publicado: (2016)

Semiphysiologically based pharmacokinetic model for midazolam and CYP3A mediated metabolite 1‐OH‐midazolam in morbidly obese and weight loss surgery patients
por: Brill, MJE, et al.
Publicado: (2015)

The Influence of Drug Properties and Ontogeny of Transporters on Pediatric Renal Clearance through Glomerular Filtration and Active Secretion: a Simulation-Based Study
por: Cristea, Sînziana, et al.
Publicado: (2020)

Asthma medication in children who are overweight/obese: justified treatment?
por: Lentferink, Yvette E., et al.
Publicado: (2019)

A Follow-up Study on BMI-SDS and Insulin Resistance in Overweight and Obese Children at Risk for Type 2 Diabetes Mellitus
por: Fazeli Farsani, Soulmaz, et al.
Publicado: (2015)

Chloroquine for SARS-CoV-2: Implications of Its Unique Pharmacokinetic and Safety Properties
por: Smit, Cornelis, et al.
Publicado: (2020)

Integration of pharmacometabolomics with pharmacokinetics and pharmacodynamics: towards personalized drug therapy
por: Kantae, Vasudev, et al.
Publicado: (2016)

The role of population PK–PD modelling in paediatric clinical research
por: De Cock, Roosmarijn F. W., et al.
Publicado: (2010)

Population pharmacokinetics of intravenous cefotaxime indicates that higher doses are required for critically ill children
por: Hartman, Stan J. F., et al.
Publicado: (2022)

Exploring the Relationship Between Morphine Concentration and Oversedation in Children After Cardiac Surgery
por: Valkenburg, Abraham J., et al.
Publicado: (2020)

Quantifying the Pharmacodynamics of Morphine in the Treatment of Postoperative Pain in Preverbal Children
por: Goulooze, Sebastiaan C., et al.
Publicado: (2021)

Midazolam Infusion and Disease Severity Affect the Level of Sedation in Children: A Parametric Time-to-Event Analysis
por: Upadhyay, Parth J., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_h54oc7ortm8cgluqbr501rhgca