The mitochondrial RNA polymerase POLRMT promotes skin squamous cell carcinoma cell growth

RNA polymerase mitochondrial (POLRMT) expression and the potential biological functions in skin squamous cell carcinoma (SCC) were explored. We showed that POLRMT is significantly elevated in skin SCC. Genetic depletion of POLRMT, using shRNA-induced knockdown or CRISPR/Cas9-mediated knockout (KO),...

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Detalles Bibliográficos
Autores principales: Wang, Yulong, Ou, Li, Li, Xirong, Zheng, Tingyu, Zhu, Wei-pei, Li, Ping, Wu, Lijun, Zhao, Tianlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349297/
https://www.ncbi.nlm.nih.gov/pubmed/35922422
http://dx.doi.org/10.1038/s41420-022-01148-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349297/
https://www.ncbi.nlm.nih.gov/pubmed/35922422
http://dx.doi.org/10.1038/s41420-022-01148-5

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