Serum levels of IgM to phosphatidylcholine predict the response of multiple sclerosis patients to natalizumab or IFN-β

We developed an ELISA assay demonstrating the high prevalence of serum IgM to phosphatidylcholine (IgM-PC) in the first stages of multiple sclerosis (MS). We aimed to analyze the role of serum IgM-PC as a biomarker of response to treatment. Paired serum samples from 95 MS patients were obtained befo...

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Detalles Bibliográficos
Autores principales: Muñoz, Úrsula, Sebal, Cristina, Escudero, Esther, Urcelay, Elena, Arroyo, Rafael, García-Martínez, Maria A., Quintana, Francisco J., Álvarez-Lafuente, Roberto, Sádaba, Maria Cruz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349316/
https://www.ncbi.nlm.nih.gov/pubmed/35922641
http://dx.doi.org/10.1038/s41598-022-16218-y

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