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The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states
Deciphering Multiple Myeloma evolution in the whole bone marrow is key to inform curative strategies. Here, we perform spatial-longitudinal whole-exome sequencing, including 140 samples collected from 24 Multiple Myeloma patients during up to 14 years. Applying imaging-guided sampling we observe thr...
Autores principales: | Rasche, Leo, Schinke, Carolina, Maura, Francesco, Bauer, Michael A., Ashby, Cody, Deshpande, Shayu, Poos, Alexandra M., Zangari, Maurizio, Thanendrarajan, Sharmilan, Davies, Faith E., Walker, Brian A., Barlogie, Bart, Landgren, Ola, Morgan, Gareth J., van Rhee, Frits, Weinhold, Niels |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349320/ https://www.ncbi.nlm.nih.gov/pubmed/35922426 http://dx.doi.org/10.1038/s41467-022-32145-y |
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