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Dynamics of nasopharyngeal tract phageome and association with disease severity and age of patients during three waves of COVID‐19
In December 2019, several patients were hospitalized and diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, which subsequently led to a global pandemic. To date, there are no studies evaluating the relationship between the respiratory phageome and the SARS‐CoV‐2 i...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349744/ https://www.ncbi.nlm.nih.gov/pubmed/35831579 http://dx.doi.org/10.1002/jmv.27998 |
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author | Ferravante, Carlo Arslan‐Gatz, Berin S. Dell'Annunziata, Federica Palumbo, Domenico Lamberti, Jessica Alexandrova, Elena Di Rosa, Domenico Strianese, Oriana Giordano, Alessandro Palo, Luigi Giurato, Giorgio Salzano, Francesco A. Galdiero, Massimiliano Weisz, Alessandro Franci, Gianluigi Rizzo, Francesca Folliero, Veronica |
author_facet | Ferravante, Carlo Arslan‐Gatz, Berin S. Dell'Annunziata, Federica Palumbo, Domenico Lamberti, Jessica Alexandrova, Elena Di Rosa, Domenico Strianese, Oriana Giordano, Alessandro Palo, Luigi Giurato, Giorgio Salzano, Francesco A. Galdiero, Massimiliano Weisz, Alessandro Franci, Gianluigi Rizzo, Francesca Folliero, Veronica |
author_sort | Ferravante, Carlo |
collection | PubMed |
description | In December 2019, several patients were hospitalized and diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, which subsequently led to a global pandemic. To date, there are no studies evaluating the relationship between the respiratory phageome and the SARS‐CoV‐2 infection. The current study investigated the phageome profiles in the nasopharyngeal swabs collected from 55 patients during the three different waves of coronavirus disease 2019 (COVID‐19) in the Campania Region (Southern Italy). Data obtained from the taxonomic profiling show that phage families belonging to the order Caudovirales have a high abundance in the patient samples. Moreover, the severity of the COVID‐19 infection seems to be correlated with the phage abundance. |
format | Online Article Text |
id | pubmed-9349744 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93497442022-08-04 Dynamics of nasopharyngeal tract phageome and association with disease severity and age of patients during three waves of COVID‐19 Ferravante, Carlo Arslan‐Gatz, Berin S. Dell'Annunziata, Federica Palumbo, Domenico Lamberti, Jessica Alexandrova, Elena Di Rosa, Domenico Strianese, Oriana Giordano, Alessandro Palo, Luigi Giurato, Giorgio Salzano, Francesco A. Galdiero, Massimiliano Weisz, Alessandro Franci, Gianluigi Rizzo, Francesca Folliero, Veronica J Med Virol Short Communications In December 2019, several patients were hospitalized and diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, which subsequently led to a global pandemic. To date, there are no studies evaluating the relationship between the respiratory phageome and the SARS‐CoV‐2 infection. The current study investigated the phageome profiles in the nasopharyngeal swabs collected from 55 patients during the three different waves of coronavirus disease 2019 (COVID‐19) in the Campania Region (Southern Italy). Data obtained from the taxonomic profiling show that phage families belonging to the order Caudovirales have a high abundance in the patient samples. Moreover, the severity of the COVID‐19 infection seems to be correlated with the phage abundance. John Wiley and Sons Inc. 2022-07-25 2022-11 /pmc/articles/PMC9349744/ /pubmed/35831579 http://dx.doi.org/10.1002/jmv.27998 Text en © 2022 The Authors. Journal of Medical Virology published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Communications Ferravante, Carlo Arslan‐Gatz, Berin S. Dell'Annunziata, Federica Palumbo, Domenico Lamberti, Jessica Alexandrova, Elena Di Rosa, Domenico Strianese, Oriana Giordano, Alessandro Palo, Luigi Giurato, Giorgio Salzano, Francesco A. Galdiero, Massimiliano Weisz, Alessandro Franci, Gianluigi Rizzo, Francesca Folliero, Veronica Dynamics of nasopharyngeal tract phageome and association with disease severity and age of patients during three waves of COVID‐19 |
title | Dynamics of nasopharyngeal tract phageome and association with disease severity and age of patients during three waves of COVID‐19 |
title_full | Dynamics of nasopharyngeal tract phageome and association with disease severity and age of patients during three waves of COVID‐19 |
title_fullStr | Dynamics of nasopharyngeal tract phageome and association with disease severity and age of patients during three waves of COVID‐19 |
title_full_unstemmed | Dynamics of nasopharyngeal tract phageome and association with disease severity and age of patients during three waves of COVID‐19 |
title_short | Dynamics of nasopharyngeal tract phageome and association with disease severity and age of patients during three waves of COVID‐19 |
title_sort | dynamics of nasopharyngeal tract phageome and association with disease severity and age of patients during three waves of covid‐19 |
topic | Short Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349744/ https://www.ncbi.nlm.nih.gov/pubmed/35831579 http://dx.doi.org/10.1002/jmv.27998 |
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