Rapid Antigen Diagnostics as Frontline Testing in the COVID‐19 Pandemic

The ongoing global COVID‐19 pandemic, caused by the SARS‐CoV‐2 virus, has resulted in significant loss of life since December 2019. Timely and precise virus detection has been proven as an effective solution to reduce the spread of the virus and to track the epidemic. Rapid antigen diagnostics has p...

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Autores principales: Xu, Jiang, Kerr, Liam, Jiang, Yue, Suo, Wenhao, Zhang, Lei, Lao, Taotao, Chen, Yuxin, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Perspectives
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349911/
https://www.ncbi.nlm.nih.gov/pubmed/35942171
http://dx.doi.org/10.1002/smsc.202200009
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author Xu, Jiang
Kerr, Liam
Jiang, Yue
Suo, Wenhao
Zhang, Lei
Lao, Taotao
Chen, Yuxin
Zhang, Yan
author_facet Xu, Jiang
Kerr, Liam
Jiang, Yue
Suo, Wenhao
Zhang, Lei
Lao, Taotao
Chen, Yuxin
Zhang, Yan
author_sort Xu, Jiang
collection PubMed
description The ongoing global COVID‐19 pandemic, caused by the SARS‐CoV‐2 virus, has resulted in significant loss of life since December 2019. Timely and precise virus detection has been proven as an effective solution to reduce the spread of the virus and to track the epidemic. Rapid antigen diagnostics has played a significant role in the frontline of COVID‐19 testing because of its convenience, low cost, and high accuracy. Herein, different types of recently innovated in‐lab and commercial antigen diagnostic technologies with emphasis on the strengths and limitations of these technologies including the limit of detection, sensitivity, specificity, affordability, and usability are systematically reviewed. The perspectives of assay development are looked into.
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spelling pubmed-93499112022-08-04 Rapid Antigen Diagnostics as Frontline Testing in the COVID‐19 Pandemic Xu, Jiang Kerr, Liam Jiang, Yue Suo, Wenhao Zhang, Lei Lao, Taotao Chen, Yuxin Zhang, Yan Small Sci Perspectives The ongoing global COVID‐19 pandemic, caused by the SARS‐CoV‐2 virus, has resulted in significant loss of life since December 2019. Timely and precise virus detection has been proven as an effective solution to reduce the spread of the virus and to track the epidemic. Rapid antigen diagnostics has played a significant role in the frontline of COVID‐19 testing because of its convenience, low cost, and high accuracy. Herein, different types of recently innovated in‐lab and commercial antigen diagnostic technologies with emphasis on the strengths and limitations of these technologies including the limit of detection, sensitivity, specificity, affordability, and usability are systematically reviewed. The perspectives of assay development are looked into. John Wiley and Sons Inc. 2022-07-05 2022-08 /pmc/articles/PMC9349911/ /pubmed/35942171 http://dx.doi.org/10.1002/smsc.202200009 Text en © 2022 The Authors. Small Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Perspectives
Xu, Jiang
Kerr, Liam
Jiang, Yue
Suo, Wenhao
Zhang, Lei
Lao, Taotao
Chen, Yuxin
Zhang, Yan
Rapid Antigen Diagnostics as Frontline Testing in the COVID‐19 Pandemic
title Rapid Antigen Diagnostics as Frontline Testing in the COVID‐19 Pandemic
title_full Rapid Antigen Diagnostics as Frontline Testing in the COVID‐19 Pandemic
title_fullStr Rapid Antigen Diagnostics as Frontline Testing in the COVID‐19 Pandemic
title_full_unstemmed Rapid Antigen Diagnostics as Frontline Testing in the COVID‐19 Pandemic
title_short Rapid Antigen Diagnostics as Frontline Testing in the COVID‐19 Pandemic
title_sort rapid antigen diagnostics as frontline testing in the covid‐19 pandemic
topic Perspectives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9349911/
https://www.ncbi.nlm.nih.gov/pubmed/35942171
http://dx.doi.org/10.1002/smsc.202200009
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