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Human cardiac organoids to model COVID‐19 cytokine storm induced cardiac injuries

Acute cardiac injuries occur in 20%–25% of hospitalized COVID‐19 patients. Herein, we demonstrate that human cardiac organoids (hCOs) are a viable platform to model the cardiac injuries caused by COVID‐19 hyperinflammation. As IL‐1β is an upstream cytokine and a core COVID‐19 signature cytokine, it...

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Detalles Bibliográficos
Autores principales: Arhontoulis, Dimitrios C., Kerr, Charles M., Richards, Dylan, Tjen, Kelsey, Hyams, Nathaniel, Jones, Jefferey A., Deleon‐Pennell, Kristine, Menick, Donald, Bräuninger, Hanna, Lindner, Diana, Westermann, Dirk, Mei, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350263/
https://www.ncbi.nlm.nih.gov/pubmed/35689600
http://dx.doi.org/10.1002/term.3327