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Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein

The worldwide spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the repeated emergence of variants of concern. For the Omicron variant, sub-lineages BA.1 and BA.2, respectively, contain 33 and 29 nonsynonymous and indel spike protein mutations. These amino acid substi...

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Detalles Bibliográficos
Autores principales: Javanmardi, Kamyab, Segall-Shapiro, Thomas H., Chou, Chia-Wei, Boutz, Daniel R., Olsen, Randall J., Xie, Xuping, Xia, Hongjie, Shi, Pei-Yong, Johnson, Charlie D., Annapareddy, Ankur, Weaver, Scott, Musser, James M., Ellington, Andrew D., Finkelstein, Ilya J., Gollihar, Jimmy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350683/
https://www.ncbi.nlm.nih.gov/pubmed/35988543
http://dx.doi.org/10.1016/j.chom.2022.07.016

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