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Mitochondria-targeted alginate/triphenylphosphonium-grafted-chitosan for treatment of hepatocellular carcinoma

Mitochondrial targeting of anticancer drugs can effectively eradicate chemotherapy-refractory cells through different mechanisms. This work presents the rational designing of mitochondria-targeted core–shell polymeric nanoparticles (NPs) for efficient delivery of doxorubicin (DOX) to the hepatic car...

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Detalles Bibliográficos
Autores principales: Arafa, Kholoud K., Hamzawy, Mohamed A., Mousa, Shaker A., El-Sherbiny, Ibrahim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350814/
https://www.ncbi.nlm.nih.gov/pubmed/35975035
http://dx.doi.org/10.1039/d2ra03240f