GABA tonic currents and glial cells are altered during epileptogenesis in a mouse model of Dravet syndrome

Dravet Syndrome (DS) is a rare autosomic encephalopathy with epilepsy linked to Na(v)1.1 channel mutations and defective GABAergic signaling. Effective therapies for this syndrome are lacking, urging a better comprehension of the mechanisms involved. In a recognized mouse model of DS, we studied GAB...

Descripción completa

Detalles Bibliográficos
Autores principales: Goisis, Rosa Chiara, Chiavegato, Angela, Gomez-Gonzalo, Marta, Marcon, Iacopo, Requie, Linda Maria, Scholze, Petra, Carmignoto, Giorgio, Losi, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350930/
https://www.ncbi.nlm.nih.gov/pubmed/35936501
http://dx.doi.org/10.3389/fncel.2022.919493

Ejemplares similares

Ejemplares similares