Liver kinase B1 in exosomes inhibits immune checkpoint programmed death ligand 1 and metastatic progression of intrahepatic cholangiocarcinoma

The increasing morbidity and high mortality of intrahepatic cholangiocarcinoma (ICC) has led to the urgent need for new diagnostics and therapeutics. Liver kinase B1 (LKB1) exerts a tumor suppressor role in multiple malignances, while its regulatory role in exosomes secreted by ICC cells is obscure....

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Detalles Bibliográficos
Autores principales: Liu, Zhuo, Zhou, Kunyan, Zeng, Jian, Zhou, Xin, Li, Huanyu, Peng, Ke, Liu, Xiang, Li, Feng, Jiang, Bin, Zhao, Ming, Ma, Tiexiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350976/
https://www.ncbi.nlm.nih.gov/pubmed/35856436
http://dx.doi.org/10.3892/or.2022.8367

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