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Anti-oncogenic and pro-myogenic action of the MKK6/p38/AKT axis induced by targeting MEK/ERK in embryonal rhabdomyosarcoma

Insights into the molecular and cellular biology of embryonal rhabdomyosarcoma (ERMS), an aggressive paediatric tumour, are required in order to identify new targets for novel treatments that may benefit patients with this disease. The present study examined the functional effects of MKK3 and MKK6,...

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Detalles Bibliográficos
Autores principales: Di Rocco, Agnese, Camero, Simona, Benedetti, Anna, Lozanoska-Ochser, Biliana, Megiorni, Francesca, Marchese, Cinzia, Stramucci, Lorenzo, Ciccarelli, Carmela, Bouché, Marina, Bossi, Gianluca, Marampon, Francesco, Zani, Bianca Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350981/
https://www.ncbi.nlm.nih.gov/pubmed/35801577
http://dx.doi.org/10.3892/or.2022.8363