Probing the cell delivery of synthetic diubiquitin chains

In this study, the live-cell delivery of structurally different synthetic diubiquitin chains was examined. We found that the combination of structural variations of the Ub chains (intrinsic factors); nature of CPP and CPP-protein linkage (extrinsic factors) influence their delivery.

Detalles Bibliográficos
Autores principales: Mandal, Shaswati, Brik, Ashraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350984/
https://www.ncbi.nlm.nih.gov/pubmed/35837864
http://dx.doi.org/10.1039/d2cc02476d
Descripción
Sumario:In this study, the live-cell delivery of structurally different synthetic diubiquitin chains was examined. We found that the combination of structural variations of the Ub chains (intrinsic factors); nature of CPP and CPP-protein linkage (extrinsic factors) influence their delivery.

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