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High-frequency repetitive transcranial magnetic stimulation (rTMS) protects against ischemic stroke by inhibiting M1 microglia polarization through let-7b-5p/HMGA2/NF-κB signaling pathway
BACKGROUND: Microglia assume opposite phenotypes in response to ischemic brain injury, exerting neurotoxic and neuroprotective effects under different ischemic stages. Modulating M1/M2 polarization is a potential therapy for treating ischemic stroke. Repetitive transcranial magnetic stimulation (rTM...
Autores principales: | Hong, Ye, Lyu, Jinfeng, Zhu, Lin, Wang, Xixi, Peng, Mengna, Chen, Xiangliang, Deng, Qiwen, Gao, Jie, Yuan, Zhenhua, Wang, Di, Xu, Gelin, Xu, Mengyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351069/ https://www.ncbi.nlm.nih.gov/pubmed/35927640 http://dx.doi.org/10.1186/s12868-022-00735-7 |
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