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Genes expressed at low levels raise false discovery rates in RNA samples contaminated with genomic DNA
BACKGROUND: RNA preparations contaminated with genomic DNA (gDNA) are frequently disregarded by RNA-seq studies. Such contamination may generate false results; however, their effect on the outcomes of RNA-seq analyses is unknown. To address this gap in our knowledge, here we added different concentr...
Autores principales: | Li, Xiangnan, Zhang, Peipei, Wang, Haijian, Yu, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351092/ https://www.ncbi.nlm.nih.gov/pubmed/35922750 http://dx.doi.org/10.1186/s12864-022-08785-1 |
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