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Overexpressing HPGDS in adipose-derived mesenchymal stem cells reduces inflammatory state and improves wound healing in type 2 diabetic mice

BACKGROUND: In diabetes, delayed wound healing was considered as the result of excessive recruitment and retention of pro-inflammatory cells and factors. Hematopoietic prostaglandin D synthase (HPGDS) was identified from differently expressed genes of diabetic human foot skin. HPGDS is responsible f...

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Detalles Bibliográficos
Autores principales: Ouyang, Long, Qiu, Daojing, Fu, Xin, Wu, Aiping, Yang, Pengyuan, Yang, Zhigang, Wang, Qian, Yan, Li, Xiao, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351105/
https://www.ncbi.nlm.nih.gov/pubmed/35922870
http://dx.doi.org/10.1186/s13287-022-03082-w