Downregulation of DNA methyltransferase-3a ameliorates the osteogenic differentiation ability of adipose-derived stem cells in diabetic osteoporosis via Wnt/β-catenin signaling pathway

BACKGROUND: Diabetes-related osteoporosis (DOP) is a chronic disease caused by the high glucose environment that induces a metabolic disorder of osteocytes and osteoblast-associated mesenchymal stem cells. The processes of bone defect repair and regeneration become extremely difficult with DOP. Adip...

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Detalles Bibliográficos
Autores principales: Zhang, Maorui, Gao, Yujin, Li, Qing, Cao, Huayue, Yang, Jianghua, Cai, Xiaoxiao, Xiao, Jingang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351106/
https://www.ncbi.nlm.nih.gov/pubmed/35927735
http://dx.doi.org/10.1186/s13287-022-03088-4

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