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Quality of life improving after propranolol treatment in patients with Infantile Hemangiomas
Infantile hemangiomas may affect the quality of life (QoL) of patients and their family members, as anxiety and worry may commonly occur in parents, also linked to the social adversion they experience. We underline the beneficial impact of oral propranolol therapy on QoL of patients with infantile h...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351120/ https://www.ncbi.nlm.nih.gov/pubmed/35927685 http://dx.doi.org/10.1186/s13052-022-01334-2 |
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author | Pensabene, Marco Di Pace, Maria Rita Baldanza, Fabio Grasso, Francesco Patti, Maria Sergio, Maria La Placa, Simona Giuffre’, Mario Serra, Gregorio Casuccio, Alessandra Cimador, Marcello |
author_facet | Pensabene, Marco Di Pace, Maria Rita Baldanza, Fabio Grasso, Francesco Patti, Maria Sergio, Maria La Placa, Simona Giuffre’, Mario Serra, Gregorio Casuccio, Alessandra Cimador, Marcello |
author_sort | Pensabene, Marco |
collection | PubMed |
description | Infantile hemangiomas may affect the quality of life (QoL) of patients and their family members, as anxiety and worry may commonly occur in parents, also linked to the social adversion they experience. We underline the beneficial impact of oral propranolol therapy on QoL of patients with infantile hemangiomas (IH) and of their relatives. A specific questionnaire measuring QoL was administered to parents of IH patients at beginning and end of a treatment with oral propranolol. Different aspects were investigated: site of the lesion, age of patients at starting therapy, length of treatment, occurrence of adverse effects and persistence/recurrence of the vascular anomaly. In all cases the questionnaire revealed a significant improvement of QoL, which was independent from all analyzed factors. It showed that oral propranolol administration in these patients combines optimal clinical results with relevant improvement of QoL, especially in cases of early management. The improvement of QoL seems unrelated to site of lesion, timing and duration of therapy, occurrence of drug-related adverse effects and persistence/recurrence of disease. |
format | Online Article Text |
id | pubmed-9351120 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-93511202022-08-05 Quality of life improving after propranolol treatment in patients with Infantile Hemangiomas Pensabene, Marco Di Pace, Maria Rita Baldanza, Fabio Grasso, Francesco Patti, Maria Sergio, Maria La Placa, Simona Giuffre’, Mario Serra, Gregorio Casuccio, Alessandra Cimador, Marcello Ital J Pediatr Letter to the Editor Infantile hemangiomas may affect the quality of life (QoL) of patients and their family members, as anxiety and worry may commonly occur in parents, also linked to the social adversion they experience. We underline the beneficial impact of oral propranolol therapy on QoL of patients with infantile hemangiomas (IH) and of their relatives. A specific questionnaire measuring QoL was administered to parents of IH patients at beginning and end of a treatment with oral propranolol. Different aspects were investigated: site of the lesion, age of patients at starting therapy, length of treatment, occurrence of adverse effects and persistence/recurrence of the vascular anomaly. In all cases the questionnaire revealed a significant improvement of QoL, which was independent from all analyzed factors. It showed that oral propranolol administration in these patients combines optimal clinical results with relevant improvement of QoL, especially in cases of early management. The improvement of QoL seems unrelated to site of lesion, timing and duration of therapy, occurrence of drug-related adverse effects and persistence/recurrence of disease. BioMed Central 2022-08-04 /pmc/articles/PMC9351120/ /pubmed/35927685 http://dx.doi.org/10.1186/s13052-022-01334-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Letter to the Editor Pensabene, Marco Di Pace, Maria Rita Baldanza, Fabio Grasso, Francesco Patti, Maria Sergio, Maria La Placa, Simona Giuffre’, Mario Serra, Gregorio Casuccio, Alessandra Cimador, Marcello Quality of life improving after propranolol treatment in patients with Infantile Hemangiomas |
title | Quality of life improving after propranolol treatment in patients with Infantile Hemangiomas |
title_full | Quality of life improving after propranolol treatment in patients with Infantile Hemangiomas |
title_fullStr | Quality of life improving after propranolol treatment in patients with Infantile Hemangiomas |
title_full_unstemmed | Quality of life improving after propranolol treatment in patients with Infantile Hemangiomas |
title_short | Quality of life improving after propranolol treatment in patients with Infantile Hemangiomas |
title_sort | quality of life improving after propranolol treatment in patients with infantile hemangiomas |
topic | Letter to the Editor |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351120/ https://www.ncbi.nlm.nih.gov/pubmed/35927685 http://dx.doi.org/10.1186/s13052-022-01334-2 |
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