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Nintedanib modulates type III collagen turnover in viable precision-cut lung slices from bleomycin-treated rats and patients with pulmonary fibrosis

BACKGROUND: Aberrant extracellular matrix (ECM) deposition and remodelling is important in the disease pathogenesis of pulmonary fibrosis (PF). We characterised neoepitope biomarkers released by ECM turnover in lung tissue from bleomycin-treated rats and patients with PF and analysed the effects of...

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Detalles Bibliográficos
Autores principales:	Hesse, Christina, Beneke, Valerie, Konzok, Sebastian, Diefenbach, Claudia, Bülow Sand, Jannie Marie, Rønnow, Sarah Rank, Karsdal, Morten Asser, Jonigk, Danny, Sewald, Katherina, Braun, Armin, Leeming, Diana Julie, Wollin, Lutz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351157/ https://www.ncbi.nlm.nih.gov/pubmed/35927669 http://dx.doi.org/10.1186/s12931-022-02116-4

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