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Propofol enhances stem-like properties of glioma via GABA(A)R‐dependent Src modulation of ZDHHC5-EZH2 palmitoylation mechanism

BACKGROUND: Propofol is a commonly used anesthetic. However, its effects on glioma growth and recurrence remain largely unknown. METHODS: The effect of propofol on glioma growth was demonstrated by a series of in vitro and in vivo experiments (spheroidal formation assay, western blotting, and xenogr...

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Detalles Bibliográficos
Autores principales: Fan, Xiaoqing, Gong, Meiting, Yu, Huihan, Yang, Haoran, Wang, Sheng, Wang, Ruiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351178/
https://www.ncbi.nlm.nih.gov/pubmed/35927718
http://dx.doi.org/10.1186/s13287-022-03087-5

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