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Propofol enhances stem-like properties of glioma via GABA(A)R‐dependent Src modulation of ZDHHC5-EZH2 palmitoylation mechanism
BACKGROUND: Propofol is a commonly used anesthetic. However, its effects on glioma growth and recurrence remain largely unknown. METHODS: The effect of propofol on glioma growth was demonstrated by a series of in vitro and in vivo experiments (spheroidal formation assay, western blotting, and xenogr...
Autores principales: | Fan, Xiaoqing, Gong, Meiting, Yu, Huihan, Yang, Haoran, Wang, Sheng, Wang, Ruiting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351178/ https://www.ncbi.nlm.nih.gov/pubmed/35927718 http://dx.doi.org/10.1186/s13287-022-03087-5 |
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