Mesenchymal stem cell-derived extracellular vesicles protect retina in a mouse model of retinitis pigmentosa by anti-inflammation through miR-146a-Nr4a3 axis

BACKGROUND: Retinitis pigmentosa is a rod-cone degenerative disease that induces irreversible vision loss. This study probed the protective capacity of mesenchymal stem cell-derived small EVs (MSC-EVs) on the retinas of rd10 mice and the underlying mechanism. METHODS: MSC-EVs were injected into the...

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Detalles Bibliográficos
Autores principales: Zhang, Jia, Li, Pengdong, Zhao, Guifang, He, Siqi, Xu, Di, Jiang, Weijie, Peng, Qian, Li, Zhaohui, Xie, Zhongjian, Zhang, Han, Xu, Ying, Qi, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351183/
https://www.ncbi.nlm.nih.gov/pubmed/35922863
http://dx.doi.org/10.1186/s13287-022-03100-x

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