Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development

Ribosomal RNA (rRNA) transcription by RNA polymerase I (Pol I) is a critical rate-limiting step in ribosome biogenesis, which is essential for cell survival. Despite its global function, disruptions in ribosome biogenesis cause tissue-specific birth defects called ribosomopathies, which frequently a...

Descripción completa

Detalles Bibliográficos
Autores principales: Falcon, Karla T., Watt, Kristin E. N., Dash, Soma, Zhao, Ruonan, Sakai, Daisuke, Moore, Emma L., Fitriasari, Sharien, Childers, Melissa, Sardiu, Mihaela E., Swanson, Selene, Tsuchiya, Dai, Unruh, Jay, Bugarinovic, George, Li, Lin, Shiang, Rita, Achilleos, Annita, Dixon, Jill, Dixon, Michael J., Trainor, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351356/
https://www.ncbi.nlm.nih.gov/pubmed/35881792
http://dx.doi.org/10.1073/pnas.2116974119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351356/
https://www.ncbi.nlm.nih.gov/pubmed/35881792
http://dx.doi.org/10.1073/pnas.2116974119

Ejemplares similares