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Mitigation of age-dependent accumulation of defective mitochondrial genomes

Unknown processes promote the accumulation of mitochondrial DNA (mtDNA) mutations during aging. Accumulation of defective mitochondrial genomes is thought to promote the progression of heteroplasmic mitochondrial diseases and degenerative changes with natural aging. We used a heteroplasmic Drosophil...

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Detalles Bibliográficos
Autores principales:	Tsai, Pei-I, Korotkevich, Ekaterina, O’Farrell, Patrick H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351377/ https://www.ncbi.nlm.nih.gov/pubmed/35881807 http://dx.doi.org/10.1073/pnas.2119009119

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