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Stochastic particle unbinding modulates growth dynamics and size of transcription factor condensates in living cells
Liquid–liquid phase separation (LLPS) is emerging as a key physical principle for biological organization inside living cells, forming condensates that play important regulatory roles. Inside living nuclei, transcription factor (TF) condensates regulate transcriptional initiation and amplify the tra...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351496/ https://www.ncbi.nlm.nih.gov/pubmed/35881789 http://dx.doi.org/10.1073/pnas.2200667119 |