Stochastic particle unbinding modulates growth dynamics and size of transcription factor condensates in living cells

Liquid–liquid phase separation (LLPS) is emerging as a key physical principle for biological organization inside living cells, forming condensates that play important regulatory roles. Inside living nuclei, transcription factor (TF) condensates regulate transcriptional initiation and amplify the tra...

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Detalles Bibliográficos
Autores principales: Muñoz-Gil, Gorka, Romero-Aristizabal, Catalina, Mateos, Nicolas, Campelo, Felix, de Llobet Cucalon, Lara I., Beato, Miguel, Lewenstein, Maciej, Garcia-Parajo, Maria F., Torreno-Pina, Juan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351496/
https://www.ncbi.nlm.nih.gov/pubmed/35881789
http://dx.doi.org/10.1073/pnas.2200667119

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