Crystal structure of the Ate1 arginyl-tRNA-protein transferase and arginylation of N-degron substrates

N-degron pathways are proteolytic systems that target proteins bearing N-terminal (Nt) degradation signals (degrons) called N-degrons. Nt-Arg of a protein is among Nt-residues that can be recognized as destabilizing ones by the Arg/N-degron pathway. A proteolytic cleavage of a protein can generate A...

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Detalles Bibliográficos
Autores principales: Kim, Bong Heon, Kim, Min Kyung, Oh, Sun Joo, Nguyen, Kha The, Kim, Jun Hoe, Varshavsky, Alexander, Hwang, Cheol-Sang, Song, Hyun Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351520/
https://www.ncbi.nlm.nih.gov/pubmed/35878037
http://dx.doi.org/10.1073/pnas.2209597119

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