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Natural Evolution Provides Strong Hints about Laboratory Evolution of Designer Enzymes
Laboratory evolution combined with computational enzyme design provides the opportunity to generate novel biocatalysts. Nevertheless, it has been challenging to understand how laboratory evolution optimizes designer enzymes by introducing seemingly random mutations. A typical enzyme optimized with l...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351539/ https://www.ncbi.nlm.nih.gov/pubmed/35901204 http://dx.doi.org/10.1073/pnas.2207904119 |