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Evaluation of the immunogenicity of auxotrophic Lactobacillus with CRISPR-Cas9D10A system-mediated chromosomal editing to express porcine rotavirus capsid protein VP4

Porcine rotavirus (PoRV) is an important pathogen, leading to the occurrence of viral diarrhoea . As the infection displays obvious enterotropism, intestinal mucosal immunity is the significant line of defence against pathogen invasion. Moreover, as lactic acid bacteria (LAB) show acid resistance, b...

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Detalles Bibliográficos
Autores principales:	Li, Fengsai, Mei, Zhuyuan, Ju, Ning, Sui, Ling, Fan, Xiaolong, Wang, Zi, Li, Jiaxuan, Jiang, Yanping, Cui, Wen, Shan, Zhifu, Zhou, Han, Wang, Li, Qiao, Xinyuan, Tang, Lijie, Wang, Xiaona, Li, Yijing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351582/ https://www.ncbi.nlm.nih.gov/pubmed/35920261 http://dx.doi.org/10.1080/21505594.2022.2107646

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