Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions

As a follow-up to the 2008 state-of-the-art (SOTA) conference on traumatic brain injuries (TBIs), the 2015 event organized by the United States Department of Veterans Affairs (VA) Office of Research and Development (ORD) analysed the knowledge gained over the last 7 years as it relates to basic scie...

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Autores principales: Cernak, Ibolja, Stein, Donald G., Elder, Gregory A., Ahlers, Stephn, Curley, Kenneth, DePalma, Ralph G., Duda, John, Ikonomovic, Milos, Iverson, Grant L., Kobeissy, Firas, Koliatsos, Vassilis E., Leggieri, Michael J., Pacifico, Anthony M., Smith, Douglas H., Swanson, Raymond, Thompson, Floyd J., Tortella, Frank C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351990/
https://www.ncbi.nlm.nih.gov/pubmed/28981339
http://dx.doi.org/10.1080/02699052.2016.1274779
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author Cernak, Ibolja
Stein, Donald G.
Elder, Gregory A.
Ahlers, Stephn
Curley, Kenneth
DePalma, Ralph G.
Duda, John
Ikonomovic, Milos
Iverson, Grant L.
Kobeissy, Firas
Koliatsos, Vassilis E.
Leggieri, Michael J.
Pacifico, Anthony M.
Smith, Douglas H.
Swanson, Raymond
Thompson, Floyd J.
Tortella, Frank C.
author_facet Cernak, Ibolja
Stein, Donald G.
Elder, Gregory A.
Ahlers, Stephn
Curley, Kenneth
DePalma, Ralph G.
Duda, John
Ikonomovic, Milos
Iverson, Grant L.
Kobeissy, Firas
Koliatsos, Vassilis E.
Leggieri, Michael J.
Pacifico, Anthony M.
Smith, Douglas H.
Swanson, Raymond
Thompson, Floyd J.
Tortella, Frank C.
author_sort Cernak, Ibolja
collection PubMed
description As a follow-up to the 2008 state-of-the-art (SOTA) conference on traumatic brain injuries (TBIs), the 2015 event organized by the United States Department of Veterans Affairs (VA) Office of Research and Development (ORD) analysed the knowledge gained over the last 7 years as it relates to basic scientific methods, experimental findings, diagnosis, therapy, and rehabilitation of TBIs and blast-induced neurotraumas (BINTs). The current article summarizes the discussions and recommendations of the scientific panel attending the Preclinical Modeling and Therapeutic Development Workshop of the conference, with special emphasis on factors slowing research progress and recommendations for ways of addressing the most significant pitfalls.
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spelling pubmed-93519902022-08-04 Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions Cernak, Ibolja Stein, Donald G. Elder, Gregory A. Ahlers, Stephn Curley, Kenneth DePalma, Ralph G. Duda, John Ikonomovic, Milos Iverson, Grant L. Kobeissy, Firas Koliatsos, Vassilis E. Leggieri, Michael J. Pacifico, Anthony M. Smith, Douglas H. Swanson, Raymond Thompson, Floyd J. Tortella, Frank C. Brain Inj Article As a follow-up to the 2008 state-of-the-art (SOTA) conference on traumatic brain injuries (TBIs), the 2015 event organized by the United States Department of Veterans Affairs (VA) Office of Research and Development (ORD) analysed the knowledge gained over the last 7 years as it relates to basic scientific methods, experimental findings, diagnosis, therapy, and rehabilitation of TBIs and blast-induced neurotraumas (BINTs). The current article summarizes the discussions and recommendations of the scientific panel attending the Preclinical Modeling and Therapeutic Development Workshop of the conference, with special emphasis on factors slowing research progress and recommendations for ways of addressing the most significant pitfalls. 2017 /pmc/articles/PMC9351990/ /pubmed/28981339 http://dx.doi.org/10.1080/02699052.2016.1274779 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Article
Cernak, Ibolja
Stein, Donald G.
Elder, Gregory A.
Ahlers, Stephn
Curley, Kenneth
DePalma, Ralph G.
Duda, John
Ikonomovic, Milos
Iverson, Grant L.
Kobeissy, Firas
Koliatsos, Vassilis E.
Leggieri, Michael J.
Pacifico, Anthony M.
Smith, Douglas H.
Swanson, Raymond
Thompson, Floyd J.
Tortella, Frank C.
Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions
title Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions
title_full Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions
title_fullStr Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions
title_full_unstemmed Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions
title_short Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions
title_sort preclinical modelling of militarily relevant traumatic brain injuries: challenges and recommendations for future directions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351990/
https://www.ncbi.nlm.nih.gov/pubmed/28981339
http://dx.doi.org/10.1080/02699052.2016.1274779
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