Cargando…
Targeting lipid biosynthesis pathways for hepatitis B virus cure
Chronic hepatitis B virus (HBV) infection is characterized by the presence of high circulating levels of non-infectious lipoprotein-like HBV surface antigen (HBsAg) particles thought to contribute to chronic immune dysfunction in patients. Lipid and metabolomic analysis of humanized livers from immu...
Autores principales: | Hyrina, Anastasia, Burdette, Dara, Song, Zhijuan, Ramirez, Ricardo, Okesli-Armlovich, Ayse, Vijayakumar, Archana, Bates, Jamie, Trevaskis, James L., Fletcher, Simon P., Lee, William A., Holdorf, Meghan M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352027/ https://www.ncbi.nlm.nih.gov/pubmed/35925919 http://dx.doi.org/10.1371/journal.pone.0270273 |
Ejemplares similares
-
Combinations of an acetyl CoA carboxylase inhibitor with hepatic lipid modulating agents do not augment antifibrotic efficacy in preclinical models of NASH and fibrosis
por: Vijayakumar, Archana, et al.
Publicado: (2022) -
Characterization of a Novel Capsid Assembly Modulator for the Treatment of Chronic Hepatitis B Virus Infection
por: Burdette, Dara, et al.
Publicado: (2022) -
Enhancing the Antiviral Efficacy of RNA-Dependent RNA Polymerase Inhibition by Combination with Modulators of Pyrimidine Metabolism
por: Liu, Qi, et al.
Publicado: (2020) -
Nine Post-translational Modifications during the Biosynthesis of Cinnamycin
por: Ökesli, Ayşe, et al.
Publicado: (2011) -
Treatment-Induced Viral Cure of Hepatitis C Virus-Infected Patients Involves a Dynamic Interplay among three Important Molecular Players in Lipid Homeostasis: Circulating microRNA (miR)-24, miR-223, and Proprotein Convertase Subtilisin/Kexin Type 9
por: Hyrina, Anastasia, et al.
Publicado: (2017)