A time-course comparative clinical and immune response evaluation study between the human pathogenic Orientia tsutsugamushi strains: Karp and Gilliam in a rhesus macaque (Macaca mulatta) model

BACKGROUND: Scrub typhus is a vector-borne febrile illness caused by Orientia tsutsugamushi transmitted by the bite of Trombiculid mites. O. tsutsugamushi has a high genetic diversity and is increasingly recognized to have a wider global distribution than previously assumed. METHODOLOGY/PRINCIPLE FI...

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Detalles Bibliográficos
Autores principales: Inthawong, Manutsanun, Sunyakumthorn, Piyanate, Wongwairot, Sirima, Anantatat, Tippawan, Dunachie, Susanna J., Im-Erbsin, Rawiwan, Jones, James W., Mason, Carl J., Lugo, Luis A., Blacksell, Stuart D., Day, Nicholas P. J., Sonthayanon, Piengchan, Richards, Allen L., Paris, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352090/
https://www.ncbi.nlm.nih.gov/pubmed/35925895
http://dx.doi.org/10.1371/journal.pntd.0010611

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