Cargando…
C3aR plays both sides in regulating resistance to bacterial infections
Activation of the complement pathway results in the production of bioactive C3a, a product of C3 cleavage, which interacts with membrane-bound receptor C3aR to regulate innate immune cell function and outcome of bacterial infection. Specifically, previous research has identified mechanistically dist...
Autores principales: | Corcoran, Jesse A., Napier, Brooke A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352106/ https://www.ncbi.nlm.nih.gov/pubmed/35925892 http://dx.doi.org/10.1371/journal.ppat.1010657 |
Ejemplares similares
-
Distinct roles of the anaphylatoxin receptors C3aR, C5aR1 and C5aR2 in experimental meningococcal infections
por: Muenstermann, Marcel, et al.
Publicado: (2019) -
Playing both sides: nucleophosmin between tumor suppression and oncogenesis
por: Di Fiore, Pier Paolo
Publicado: (2008) -
Down-Regulation of C3aR/C5aR Inhibits Cell Proliferation and EMT in Hepatocellular Carcinoma
por: Chen, Bendong, et al.
Publicado: (2020) -
C3aR and C5aR1 act as key regulators of human and mouse β-cell function
por: Atanes, Patricio, et al.
Publicado: (2017) -
The “C3aR Antagonist” SB290157 is a Partial C5aR2 Agonist
por: Li, Xaria X., et al.
Publicado: (2021)