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C3aR plays both sides in regulating resistance to bacterial infections

Activation of the complement pathway results in the production of bioactive C3a, a product of C3 cleavage, which interacts with membrane-bound receptor C3aR to regulate innate immune cell function and outcome of bacterial infection. Specifically, previous research has identified mechanistically dist...

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Detalles Bibliográficos
Autores principales: Corcoran, Jesse A., Napier, Brooke A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352106/
https://www.ncbi.nlm.nih.gov/pubmed/35925892
http://dx.doi.org/10.1371/journal.ppat.1010657

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