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Hepatic transcript signatures predict atherosclerotic lesion burden prior to a 2-year high cholesterol, high fat diet challenge

The purpose of this study was to identify molecular mechanisms by which the liver influences total lesion burden in a nonhuman primate model (NHP) of cardiovascular disease with acute and chronic feeding of a high cholesterol, high fat (HCHF) diet. Baboons (47 females, 64 males) were fed a HCHF diet...

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Detalles Bibliográficos
Autores principales:	Puppala, Sobha, Spradling-Reeves, Kimberly D., Chan, Jeannie, Birnbaum, Shifra, Newman, Deborah E., Comuzzie, Anthony G., Mahaney, Michael C., VandeBerg, John L., Olivier, Michael, Cox, Laura A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352111/ https://www.ncbi.nlm.nih.gov/pubmed/35925965 http://dx.doi.org/10.1371/journal.pone.0271514

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